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Classic Southern Meatloaf Recipe: Comfort Food at Its Finest

A warm and hearty meatloaf that brings the charm of Southern kitchens to your dinner table. Packed with flavorful vegetables, rich seasonings, and topped with a tangy-sweet glaze, this meatloaf is perfect for family dinners, potlucks, or whenever you’re craving comforting home-cooked food.

Ingredients

Scale
  • 2 pounds ground beef (80/20 recommended)

  • 1 cup finely chopped yellow onion

  • ½ cup finely chopped green bell pepper

  • ½ cup finely chopped celery

  • 2 cloves garlic, minced

  • 1 cup whole milk

  • 2 large eggs

  • 1 cup plain breadcrumbs (or crushed saltine crackers)

  • 2 tablespoons Worcestershire sauce

  • 1 tablespoon Dijon mustard

  • 1 teaspoon kosher salt

  • ½ teaspoon black pepper

  • ½ teaspoon paprika

  • ¼ teaspoon cayenne pepper (optional)

For the glaze:

  • ¾ cup ketchup

  • 2 tablespoons brown sugar

  • 1 tablespoon apple cider vinegar

  • 1 teaspoon yellow mustard

Instructions

  • Preheat oven to 350°F (175°C). Line a baking sheet with parchment paper or lightly grease a loaf pan.

  • In a skillet over medium heat, sauté the onion, bell pepper, and celery in a little oil until soft, about 5–7 minutes. Add minced garlic and cook for another minute. Remove from heat and let cool slightly.

  • In a large mixing bowl, combine the ground beef, sautéed vegetables, breadcrumbs, milk, eggs, Worcestershire sauce, Dijon mustard, and all the seasonings. Mix gently until everything is just combined—avoid overmixing.

  • Shape the meat mixture into a loaf on the baking sheet or press it into the prepared loaf pan.

  • Bake for 45 minutes. While baking, prepare the glaze by mixing ketchup, brown sugar, apple cider vinegar, and mustard in a small bowl.

  • After 45 minutes, remove the meatloaf from the oven and spread the glaze over the top.

  • Return to the oven and bake for an additional 15–20 minutes, or until the internal temperature reaches 160°F (71°C).

  • Let rest for 10 minutes before slicing and serving.

Notes

  • For added richness, use a mix of ground beef and pork.

  • A dash of hot sauce can enhance the glaze’s flavor.

  • Leftover slices are perfect for sandwiches.

  • Make ahead and refrigerate overnight before baking for deeper flavor.